Wednesday, July 6, 2011
Monocistronic vs. Polycistronic mRNA
An mRNA molecule is said to be monocistronic when it contains the genetic information to translate only a single protein. This is the case for most of the eukaryotic mRNAs.[5][6] On the other hand, polycistronic mRNA carries the information of several genes, which are translated into several proteins. These proteins usually have a related function and are grouped and regulated together in an operon. Most of the mRNA found in bacteria and archea are polycistronic.[5] Dicistronic or bicistronic is the term used to describe an mRNA that encodes only two proteins.
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